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Evaluation of anti-inflammatory and pro-neural repair mechanisms of T7-LNP@YHV984 Polarization of microglia in the infarct brain region is an effective way to reduce ischemic reperfusion injury.Through immunofluorescence analysis of tMCAO mouse brain tissue, we observed that mice treated with T7-LNP@YHV984 demonstrated marked downregulation of CD16/32 expression and upregulation of CD206 expression compared to other control groups, with the T7-LNP@YHV984 group exhibiting the most notable alterations (Fig